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Coagulative necrosis is a form of necrosis in which the architecture of dead tissues is preserved for a span of at least some days.
• The affected tissues exhibit a firm texture. Presumably, the injury denatures not only structural proteins but also enzymes and so blocks the proteolysis(단백질 가수분해) of the dead cells
• Ultimately the necrotic cells are removed by phagocytosis of the cellular debris by infiltrating leukocytes and by digestion of the dead cells by the action of lysosomal enzymes of the leukocytes.
• A localized area of coagulative necrosis is called an infarct.
필기) 죽었는데 어느정도 윤곽을 유지한다.
형태를 유지해주는 단백질 +기능하는 단백질 + enzyme 하는 단백질
혈류가 끊기면 죽고, 세포의 윤곽이 남아있다
enzyme 의 작용으로, 형태를 유지하지 않는 건 대척점에 있는 liquefactive necrosis ex>뇌는 죽처럼 됨